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The Duke Clinical Research Training Program

Building on Duke’s pioneering role in biomedical research, CRTP promotes leading-edge investigative practices grounded in sound scientific principles.  For over 30 years, the program has offered highly relevant courses and mentored research that impact quantitative and methodological knowledge to conceptualize and carry out hypothesis-driven multidisciplinary research.

Through excellence in teaching, promoting reproducible research and rigorous ethics training and practice, the Clinical Research Training Program at Duke School of Medicine is committed to producing the next generation of leaders shaping  clinical research today.

Each year, 100+ students work with faculty, clinical educators, and staff who are actively engaged in exploring clinically relevant research to promote the health of patients and populations.

Housed within the Duke Department of Biostatistics and Bioinformatics, we are one of the oldest clinical research training programs in the nation and the premier degree-based educational program for training clinical researchers within the Duke University School of Medicine.

Historical Leadership

William Wilkinson, PhD (1986-2001) founded the Biometry Training Program in 1986. At the time, the program was housed in the Department of Community and Family Medicine.  Trained at the University of North Carolina at Chapel Hill, Dr. Wilkinson served as the Division Chief for the Division of Biometry within the Department.  In 1997, the program was renamed the Clinical Research Training Program to reflect the expansion of the curriculum to include health economics, health services research and research management.  The degree was updated to become the Master of Health Sciences in Clinical Research.  In a first-of-it-kind partnership with the Clinical Center at the National Institutes of Health, CRTP has been offered to NIH health professionals via videoconferencing from Duke since 1998.   In 2000, the program moved again to the newly created Department of Biostatistics and Bioinformatics with Dr. Wilkinson serving as interim chair of the Department until 2005.

Eugene Oddone, MD (2002-2012), took the reins as Director of CRTP in 2002.  A graduate of Duke Medical School, and 1992 CRTP graduate himself, Oddone expanded the program in several directions.  In 2002, a concentration in Medical Genomics was added. In 2011, CRTP partnered with the Brazilian Clinical Research Institute (BRCI) to offer the degree to Brazilian health professionals.

Steven Grambow, PhD (2012 – Present). The program has maintained its vitality and progress under Dr. Grambow who also serves as Vice-Chair of Education in the Department of Biostatistics and Bioinformatics.  A graduate of the University of Kentucky, he has been instrumental in offering several on line initiatives.

Bill Wilkinson, PhD
William Wilkinson, PhD​

Professor Emeritus
Department of Biostatistics and Bioinformatics

Eugene Oddone, MD
Eugene Oddone, MD, MHSc

Professor of Medicine
Department of Medicine

Biostatistics and Bioinformatics student and faculty portraits and group photos at Hock Plaza.
Steven Grambow, PhD

Assistant Professor
Department of Biostatistics and Bioinformatics

Gail Ladd

Program Coordinator
Clinical Research Training Program
(919) 681-4560